Nature engineers highly organized supramolecular materials across length scales. Taking inspiration from Nature (bone, teeth, …), we are investigating biomimetic systems, based on classical and non-classical pathways of mineralization, to create new materials that, through structural mimicry and tailored chemistry, display unique bioactive properties. We are using these biomimetic systems to build advanced coatings and scaffolds to induce tissue repair and regeneration.
Effects of Molecular Weight and Concentration of Poly(Acrylic Acid) on Biomimetic Mineralization of Collagen. ACS Biomaterials Science and Engineering (2018) 4, 2758-2766. Y. Qi, Z. Ye, A. Fok, B.N. Holmes, M. Espanol, M.P. Ginebra, C. Aparicio.
Biomimetic Mineralization of Recombinamer-Based Hydrogels toward Control Morphologies and High Mineral Density. ACS Applied Materials and Interfaces (2015) 7(46):25784–25792. Y. Li, X. Chen, A. Fok, J.C. Rodriguez-Cabello, C. Aparicio.