Intrafibrillar Mineralized Collagen
Intrafibrillar Mineralized Collagen
Mineralized Recombinamer
Calcium Phosphate Cement
Mineralized Recombinamer Scaffold

Nature engineers highly organized supramolecular materials across length scales. Taking inspiration from Nature (bone, teeth, …), we are investigating biomimetic systems, based on classical and non-classical pathways of mineralization, to create new materials that, through structural mimicry and tailored chemistry, display unique bioactive properties. We are using these biomimetic systems to build advanced coatings and scaffolds to induce tissue repair and regeneration.

 

Biomimetic mineralized hybrid scaffolds with antimicrobial peptides. Bioactive Materials (2021) 6(8):2250-2260. Z. Ye, X. Zhu, I. Mutreja, S.K. Boda, N.G. Fischer, A. Zhang, C. Lui, Y. Qi, C. Aparicio.

 

Bioinspired mineralization with hydroxyapatite and hierarchical natural aligned nanofibrillar cellulose. ACS Applied Materials and Interfaces (2019) 7;11(31):27598-27604. Y. Qi, C. Zheng, Z. Ye, Z. Hongli, C. Aparicio.

 

Intrafibrillar Mineralization of Self-Assembled Elastin-Like Recombinamer Fibrils. ACS Applied Materials and Interfaces (2017) 9(7):5838–5846. Y. Li, J.C. Rodriguez-Cabello, C. Aparicio.

Biomimetic Mineralization of Recombinamer-Based Hydrogels toward Control Morphologies and High Mineral Density. ACS Applied Materials and Interfaces (2015) 7(46):25784–25792. Y. Li, X. Chen, A. Fok, J.C. Rodriguez-Cabello, C. Aparicio.

 

Biomineralization and Biomaterials. Fundamentals and Applications. Woodhead Publishing. Inc. – Elsevier (2015). ISBN: 978-1-78242-338-6. Eds, C. Aparicio, M.P. Ginebra.